ModM DNA methyltransferase methylome analysis reveals a potential role for Moraxella catarrhalis phasevarions in otitis media

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Immune response to outer membrane antigens of Moraxella catarrhalis in children with otitis media.

The systemic and local antibody responses to homologous strains of Moraxella catarrhalis were investigated in 14 children with otitis media. A total of 8 children (57%) demonstrated a rise in serum antibody of the immunoglobulin G (IgG) (5 of 14), IgM (5 of 14), or IgA (6 of 14) classes of immunoglobulin to outer membrane antigens. Local antibody consisted of IgG (100%), IgM (29%), and IgA (71%...

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Acute otitis media caused by Moraxella catarrhalis: epidemiologic and clinical characteristics.

BACKGROUND This study describes the epidemiologic, microbiologic, and otologic features and selected signs and symptoms of acute otitis media (AOM) caused by Moraxella catarrhalis and compares them with AOM caused by other bacterial pathogens. METHODS Patients aged <5 years with culture-positive AOM from whom a middle ear fluid specimen was obtained and cultured during 1999-2006 were enrolled...

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Phenotypic and Genotypic Detection of Moraxella Catarrhalis Among Patients With Respiratory Tract and Otitis Media Infections

Respiratory tract infections are considerably prevalent worldwide and identifying their aetiological agents is of great medical and therapeutic value. The aims of the present study are to determine the prevalence of Moraxella catarrhalis among Sudanese patients infected with respiratory tract infections (upper and lower) and to determine the antibiotic sensitivity pattern of Moraxella catarrhal...

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Respiratory Syncytial Virus Promotes Moraxella catarrhalis-Induced Ascending Experimental Otitis Media

Otitis media (OM) is a polymicrobial disease wherein prior or concurrent infection with an upper respiratory tract virus plays an essential role, predisposing the middle ear to bacterial invasion. In episodes of acute bacterial OM, respiratory syncytial virus (RSV) is the most commonly isolated virus and thus serves as an important co-pathogen. Of the predominant bacterial agents of OM, the pat...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2014

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fj.14-256578